Platelet activation in distinct forms of coronary artery disease.
نویسنده
چکیده
Correspondência: Dikran Armaganijan • Instituto Dante Pazzanese de Cardiologia Av. Dr. Dante Pazzanese, 500 04012-180 • São Paulo, SP E-mail: [email protected] Recebido em 16/09/06 • Aceito em 16/09/06 O endotélio responde aos estímulos, modula a indução e/ou regressão de vários genes e sua atividade autócrina/parácrina responde pela atividade antiinflamatória, antimitogênica, vasodilatadora, antitrombogênica e homeostasia com os componentes intravasculares. A intensidade e a persistência da injúria vascular aumentam a expressão das moléculas de adesão derivadas da super família de seletinas (E e P). O fator nuclear de transcrição (NF) – kappa B expressa essas e outras moléculas de adesão, facilitando a entrada parietal dos monócitos aderidos no endotélio e contribuindo para a patogênese da aterosclerose.
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ورودعنوان ژورنال:
- Arquivos brasileiros de cardiologia
دوره 87 4 شماره
صفحات -
تاریخ انتشار 2006